Create a segment for sendouts for Email recipients who have not asked you to anonymize their data.
You must activate DoNotTrack and either update the information for users or set a default value for users without a DoNotTrack status.
You should select the attribute 'DoNotTrack' with the value False
Any segment you create which requires values that have been anonymized (message reply, link click, etc.) will automatically exclude contacts with DoNotTrack = true